As an elementary school student, Dr. Renee Chosed participated in her first science fair by examining the growth of plants treated with different fertilizers. Unsurprisingly, it didn't turn out to be the most daunting experiment of her professional career. But from that basic experience, she gained something invaluableā€”a passion for science.

Two decades later, that infatuation has blossomed into a scientific career as an educator and researcher. As a teacher, Dr. Chosed believes it's her responsibility to encourage students to ask questions, pursue answers and generate solutions. To achieve that, she provides her students with a basic and firm foundation that will enable them to pursue their research interests.

Dr. Chosed earned a bachelor of science in biochemistry and molecular biology from Trinity University in 2001. During her undergraduate years, she worked in the biochemistry lab of Dr. William Kurtin at Trinity University and for a summer in the SMART Program at Baylor College of Medicine in a cancer research lab.

Upon graduation from Trinity, Dr. Chosed attended graduate school at the University of Texas Southwestern Medical Center in Dallas where she was a research student in the lab of Dr. Kim Orth in the department of molecular biology. She earned a Ph.D. in biological chemistry in 2006. She then moved to Houston and was an Odyssey Postdoctoral Fellow in the lab of Dr. Sharon Dent at UT MD Anderson Cancer Center. Her first teaching experience came as a visiting assistant professor at Trinity University from 2009 to 2011. She joined Furman's faculty in 2011.

Name Title Description

BIO-140

The War on Cancer

An introduction of the basic biology of cancer and its various origins. How cancer can be prevented, diagnosed and treated will also be examined. Intended to be accessible to all students regardless of science background. May Experience ONLY. 2 credits.

BIO-221

Genetics

Introduction to the study of inheritance. Topics include: transmission of genes in cellular and organismal reproduction, structure and arrangement of genetic material in the cell, control and function of genes, and population genetics. Equal emphasis given to inheritance patterns and molecular genetics. Laboratories include testing the genetics of Drosophila and other organisms, and basic molecular techniques.

BIO-303

Biochemistry of the Cell

Study of the structure and function of biomolecules in the context of the cell. Topics include: the major biosynthetic and catabolic pathways in the cell and their regulation, protein function, structure, modifications and degradation, enzyme kinetics and selected biochemical techniques. Laboratory work involves current biochemical methods such as protein purification from various types of cells and subsequent enzymatic characterization.

BIO-461

Tch Mthds & Mtrls in Biology

Practicum for developing teaching skills in biology, including the laboratory and field work. Topics include planning and preparation, safety and storage, and instruction. Practicum will provide experiences teaching in the university classroom.

CSC-105

Intro to Computer Science

Introduction to computing through the lens of a significant problem domain. How is computing used to solve problems? What do you need to know to use computing to solve applied problems? A single potential problem is studied from domains which include the arts, sciences, education and medicine. Examples of specific topics include assistive technology, artificial intelligence, social media, social agents and robots, humanities, games or any other area that demonstrates significant computer science applications. Check out the current themes being offfered now.

The primary goal of Dr. Renee Chosed's research is to understand the role that posttranslational modifications play in disease progression. Posttranslational modifications function to regulate a variety of events in the cell including protein targeting, degradation, enzymatic activity and protein-protein interactions. Dr. Chosed is highly interested in learning how the enzymes that add and remove posttranslational modifications from target proteins are involved in various neurodegenerative diseases. Her past research has focused on the regulated removal of one posttranslational modification, SUMO, by an enzyme from a plant pathogen. She has also studied how protein methylation impacts the enzymatic activity of a large protein complex involved in transcriptional regulation. By examining the different aspects of regulation of posttranslational modifications, Dr. Chosed has developed an interest in how the modifying enzymes play a role in disease progression.

*Denotes undergraduate coauthor

  • Latham, J.A., Chosed R.J., Wang, S., Dent, S.Y. (2011) Chromatin Signaling to Kinetochores Transregulation of Dam1 Methylation by Histone H2B Ubiquitination. Cell 146(5):709-19.
  • Chosed, R., Dent, S.Y. (2007) A two-way street: LSD1 regulates chromatin boundary formation in S. pombe and Drosophila. Mol. Cell. Vol. 26(2):160-162.
  • Chosed, R., Tomchick, D.R., Brautigham, C., Mukherjee, S., Negi, V.S., Machius,M., Orth, K. (2007) Structural Analysis of Xanthomonas XopD Provides Insights into Substrate Specificity of ULPs. J. Biol. Chem. Vol. 282(9):6773-6782.
  • Chosed, R., Mukherjee, S., Lois, L.M., Orth, K. (2006) Evolution of a Signaling System that Incorporates Both Redundancy and Diversity: Arabidopsis SUMOylation. Biochemical Journal. Vol. 398:521-529.
  • Hotson, A.*, Chosed, R.,* Orth, K., Mudgett, M.B. (2003) Xanthomonas Type III Effector XopD Targets SUMO-conjugated Proteins in planta. Mol. Microbiol. Vol. 50:377-389. (*equally contributed to this work)
Education
Ph.D.
Graduate School of Biomedical Sciences, The University of Texas Southwestern Medical Center
B.S.
Trinity University

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